Patient-Focused Research

Pursuing evidence-based patient-oriented research in vulnerable populations

Infectious disease pandemics raise significant and novel challenges to the organization and practice of patient care. The Cluster Patient-focussed Research pursues research of salient patient-centred issues involved in preparing for and responding to pandemic disease, including those arising from deploying restrictive public health measures to contain and curb the spread of disease (e.g. social distancing), identification of vulnerable populations and risk, setting priorities for the allocation of scarce resources, health care workers’ duty to care in the face of heightened risk of infection, conducting clinical research during pandemics, and governance of preventing and responding to pandemic disease, guaranteeing the continuity of care for patients with chronic diseases and prevention of collateral damage (e.g. adverse effects on mental health, exacerbation of inequalities, worsening of cardiometabolic health) and promoting patient empowerment. A particularly striking characteristic of the Covid-19 pandemic has been the rapid deployment of novel digital technologies and applications. Whilst digital innovation offer great promise for patient-centred research and health care services, its safe and effective realization requires consideration of data privacy and regulatory compliance. Multidisciplinary interaction is key for not only preserving but also improving patient-centred care-approaches, self-management and autonomy.

Cluster Chair and Co-Chair

Tracking infectious diseases in menopausal women

menoBalance App: Use of AI methods to design a personalised chronic and infectious disease management medical device

Petra Stute / David Ginsbourger / Ben Spycher / Rowan Iskandar

Monitoring and characterization of Influence A in humans and pigs

An integrative One Health network to monitor and characterize influenza A viruses circulating in the human and pig population

Ronald Dijkman / Andri Rauch / Heiko Nathues / Jenna Kelly / Philipp Latzin / Manuela Funke-Chambour / Gilles Wandeler / Cédric Hirzel / Franziska Suter-Riniker

Monitoring of SARS-CoV-2 through multi-data integration

Early detection for early action: integrating multiple data sources for monitoring the SARS-CoV-2 epidemic in near real-time

Christian Althaus / Guido Beldi / Julien Riou / Raphael Sznitman / Alban Ramette / Kevin Heng / Alexander Leichtle

Tackling pneumococcal diseases with interspecies bacterial peptides

Exploring the potential of interspecies bacterial peptides for tackling pneumococcal diseases

Lucy Hathaway / Yok-Ai Que

Harnessing targeted protein degradation to unravel Theileria-induced pathology

Studying the role of Theileria-secreted proteins to understand parasite-induced pathology using protein degradation

Sven Rottenberg / Jean-Louis Reymond

Investigating Leishmania cases in Bern and Guinea, West Africa

LeishMa-Swi-Gui: A Comprehensive Study of Leishmaniasis Cases in Bern and an Investigation of Endemicity in Guinea, West Africa, focusing on Clinical and Xenosurveillance Methods

Cornelia Staehelin / Alexander Oberli / Ronald Wolf / David Leuenberger

Viral transmission (and prevention measures) in the classroom

Preparedness for surveillance in school rooms in pandemic and epidemic situations: multiple measure approach to estimate transmission and interventions for Covid-19 and seasonal influenza

Lukas Fenner / Philipp Jent / Pascal Bittel / Tina Hascher